Senior Scientist, Translational Pathology
Gaithersburg, MD
Join our Translational Pathology group within Translational Medicine's Cancer Biomarker Development Team. We are accountable for delivering timely high-quality, pre-clinical and clinical tissue-based assays, digital images, quantitative and spatial biomarker data to inform mechanistic understanding and generate novel clinicopathological insights to advance AstraZeneca's Oncology portfolio and support development of Companion Diagnostics.
Accountabilities:
As a Senior Scientist, you will be responsible for study and panel design, staining and through to digital quantitative analysis. Your role includes but is not limited to Immunohistochemistry (IHC), immunofluorescence (IF), multiplexed IHC/IF, slide digitization and digital quantitative analysis. You will generate tissue biomarker data to guide target identification, indication selection, early indication of biological activity, and patient stratification/selection in Oncology. You will also perform assay development, optimization and validation, assay interpretation and documentation.
Essential Skills/Experience:
- Minimum Bachelors' degree in relevant biological science and 3-5 years experience performing hands on immunohistochemistry, PhD in relevant biological science and at least 1 year experience performing hands on immunohistochemistry.
- Excellent organizational skills, attention to detail, and documentation practices
- Strong communication and interpersonal skills
- Proficient in use of relevant computer programs (Microsoft Office, Excel and MS Project)
Desirable Skills/Experience:
- PhD in relevant biological science
- >1 year experience using automated IHC staining platforms
- Multiplex staining, immunofluorescence and in situ hybridization experience preferred
- Biopharmaceutical industry, hospital or academic experience
- Authorship on scientific manuscripts
- Familiarity with GxP/ICH regulatory requirement
At AstraZeneca, we are a science-based, leading and decisive Oncology enterprise united in our vision to eliminate cancer as a cause of death. We push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. Our commitment to patients and pioneering spirit are truly embedded and it's what makes our pipeline unique.
About Our Gaithersburg Oncology Hub
Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.
The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.
So, what's next?
Are you ready to make a difference? Apply now to be part of our mission to eliminate cancer as a cause of death!
If you're curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.
Closing Date: October 9, 2024
Competitive remuneration and benefits apply
We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.
Where can I find out more-
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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Date Posted
12-Sep-2024Closing Date
08-Oct-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.