Job Description

Our Company Research Laboratories in South San Francisco is a premier research hub designed to foster collaboration between scientists to discover new medicines to improve human health. Retinal and Vascular Biology group within Cardiometabolic Disease Therapeutic Area is seeking a driven and creative Scientist to join our drug discovery team. This is an exciting opportunity to directly contribute to drug target identification and validation activities in close collaboration with colleagues in Biology, Chemistry and Biologics teams at our Research & Development Division South San Francisco and across broader our Research & Development Division network.

The ideal candidate will be an independent in vivo scientist with minimum of 3 years of industry experience with high level of motivation and dedication to lab experimentation with excellent comprehension of ocular biology. This position requires demonstrated proficiency in in vivo ophthalmology skills and flexibility to support in vitro assays and models in industry discovery research.

Job Responsibilities:

• Design and execute experiments for target identification and validation utilizing in vivoophthalmology disease animal models

• Directly contribute to drug discovery efforts to address high unmet medical need in ophthalmology

• Learn and establish novel platforms and technologies to advance drug discovery efforts

Qualifications:

Education:

• Bachelor's (with 3+ years) or Master's degree in cell biology, molecular biology, neuroscience or related biological discipline and relevant professional laboratory research experience listed below

Required Experience and Skills:

• Extensive hands-on experience handling laboratory animals (mice and rats)

• Technical expertise and experience in pre-clinical in vivo ophthalmology including retinal imaging techniques (fluorescein angiography, optical coherence tomography), retinal functional assays (electroretinograms) and ocular injections

• Experience in handling and processing ex-vivo tissue samples for downstream in vitro analysis

• Proficiency using data analysis and visualization software such as Excel, GraphPad Prism and Spotfire

• Ability to independently design, perform, troubleshoot, and interpret biological experiments

• Strong motivation and passion for science

• Commitment to experimental excellence and scientific rigor

• High level of organizational skills to support multiple projects in matrix environment

• Excellent oral presentation and communication skills

Preferred Experience and Skills:

• Hands on experience with building in vitro biochemical and cell-based assays utilizing state-of-art technologies

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate's relevant skills, experience, and education.

Expected US salary range:

Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here.

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Relocation:

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Travel Requirements:

Flexible Work Arrangements:

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Requisition ID:R317184