University of Michigan
Research Lab Tech Intermediate
Ann Arbor, MI
Jan 15, 2025
Full-time
Full Job Description

How to Apply

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Job Summary

The laboratory of Dr. Uhnsoo Cho in the Department of Biological Chemistry aims to understand the molecular mechanisms of epigenetic regulation and metabolic homeostasis using the structural biology as a main tool, such as protein x-ray crystallography and cryo electron microscopy (cryo-EM).

In addition, Dr. Uhnsoo Cho's lab is interested in the method development by developing new types of cryoEM grids.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world's most distinguished academic health systems.  In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

  • Excellent medical, dental and vision coverage effective on your very first day
  • 2:1 Match on retirement savings

Responsibilities*

The applicant will be involved in several research projects, and will have opportunities to make original scientific contributions, interpret and analyze results under the guidance of other senior researchers in the lab. The applicant will learn and use negative-stain electron microscopic and cryogenic electron microscopic approaches to study the architecture of the large protein complex with protein expression, purification, enzyme characterization, and image collection and processing.

Day-to-day responsibilities include:

.  Protein expression and purification using both E. coli and yeasts

.  Glycerol-gradient ultracentrifugation to purify the protein-nucleosome complexes

.  cryo-EM data collection and image processing

.  Manuscript preparation, publication and presentation of results at scientific conferences

In addition, candidates will be expected to provide lab management support in the form of routine laboratory maintenance, record keeping, and compliance with University of Michigan regulations. The candidate will also mentor and assist students with research techniques and the use of instruments to help advance the research objectives of the laboratory. We expect at least two years of lab participation in this position.

Required Qualifications*

HS Diploma or Associate Degree with at least 1-3 years experience in a laboratory setting, working closely with other senior researchers.

Desired Qualifications*

Bachelor's degree or higher is strongly preferred. Experience in mentoring undergraduate students is desirable.

Modes of Work

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.

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Job Information
Job Category:
Science
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Research Lab Tech Intermediate
University of Michigan
Ann Arbor, MI
Jan 15, 2025
Full-time
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