The Clinical Imaging Scientist/Physician will provide scientific and clinical input to all aspects of late stage product development. This includes the design, delivery, and interpretation of pivotal clinical trials and of studies that further characterize the overall benefit, risk, and value of late stage development products in the respiratory and immunology therapeutic area. The Clinical Imaging Scientist/Physician also needs to possess strong analytical skills, as you will be responsible for the quality of processes and outcomes related to Imaging endpoints. An important aspect is to be comfortable analyzing large amounts of data, to be able to identify potential data quality issues, as well as opportunities for novel analyses.

The role will have a focus on the integration of clinical imaging in late stage clinical trials and provide strategic and technical expertise on the conception and implementation of imaging endpoints which are to be included in later phases of clinical development (Phase II-III). This includes literature research and frequent interaction with internal and external key experts.

This role will also support consistent implementation of standardized imaging protocols across development programs, including training the wider clinical team. Where there is a new requirement for imaging data collection, you will work with the drug project team, internal/external key experts and imaging CROs to ensure optimal image data collection and analysis.

We are seeking a highly motivated, interactive, and creative person that possesses the ability to work across a highly matrixed environment to advance clinical drug development programs throughout the clinical development process. You will collaborate with colleagues within late stage development Respiratory & Immunology and early stage development groups.

You will work as a member of a diverse and motivated team of researchers spanning across multiple divisions and geographies within Biopharmaceuticals R&D. Clear written and verbal communication skills, as well as capability to present scientific designs and results to multidisciplinary teams and key stakeholders are required. You will work both independently and collaboratively and contribute significantly to study design, regulatory submissions, process improvements, and mentoring.

Key activities and leadership areas

Provide scientific leadership in the innovative design, execution, and interpretation of clinical trials
Be the lead medical imaging scientist/physician in a number of drug projects across the respiratory and immunology portfolio
Provide technical support to develop, implement and maintain standardized imaging protocols
Provide imaging expert input to the design, implementation and reporting of clinical studies with imaging-based end-points, including support for protocol authoring, and regulatory documents/defense
Technical input related to imaging provided to study teams may include site selection, site training, monitor training, logistics, data collection and problem solving
Provide technical input in imaging charter development, radiology manuals, site initiation, data collection, interpretation and reporting, working closely with the study teams and imaging CROs
Act as an imaging subject matter expert to help raise the level of understanding of imaging end points within clinical development - this may include imaging training & education as required
Effectively collaborate with colleagues in other functions including early and late stage Clinical Development, Biometrics, Clinical Operations, Patient Safety, Regulatory Affairs and Medical Affairs
Lead and participate in activities that ensure quality, consistency, and integration of clinical study related deliverables
Present protocol, scientific results, and other key information to multidisciplinary teams and key stakeholders, including presenting at investigator meetings
Will require International and domestic travel

Basic Qualifications

MD with imaging related specialist diploma (radiologist), and/or imaging related scientific doctoral degree (PhD), or other professional training related to clinical imaging, or science related degree with practical experience related to clinical imaging modalities (CT, MRI, PET, SPECT)
Practical experience from working with quantitative image analysis in a clinical and/or academic research setting, with an understanding of image acquisition and reconstruction protocols
Proven ability to work collaboratively in a cross-functional setting
Minium of 3 years of experience in the pharmaceutical industry.

Preferred Qualifications

For MD, at least 3 years clinical experience from a specialist position
Knowledge and experience in lung function and other physiological assessments is desired
Experience of supporting clinical trials, in particular Phase II and Phase III, preferably with an imaging component

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base salary for this position ranges from $233,290-$349,935. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

At AstraZeneca, we are dedicated to being a Great Place to Work. Our team is inclusive and diverse, working in a solution-oriented, trusting, and collaborative work environment. We are committed to improving healthcare and quality of life for patients across a wide range of diseases and disorders by developing innovative therapies. Join us in the Biopharmaceuticals R&D department and contribute to our growing pipeline!

Date Posted

01-Aug-2024

Closing Date

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.