Job Description

The Future Talent Program features internships that last up to 12 weeks and will include one or more projects.These opportunities in our Research Division can provide you with great development and a chance to see if we are the right company for your long-term goals.

Our Research & Development Division is dedicated to advance breakthrough science focused on patient needs. The Continuous & Expression Technologies (CET) group, within the Process Research & Development department, is seeking summer interns with a passion for scientific research and work collaboratively across teams. CET offer opportunities in our state-of-the-art laboratories to solve fundamental synthetic, biological or automation problems relevant to drug development and manufacturing, while functioning as fully integrated members of the company project teams.

CET is responsible for driving drug manufacture innovation across our company's diverse pipeline. CET is seeking interns in three technical areas: Novel Expression Systems (NES), Large Molecule Continuous Manufacturing Technologies (LM CMT) in both upstream and downstream processing. NES is tasked with advancing expression systems across a range of organisms that will be applied to discovery and development of novel biologics and vaccines, as well as to our engineered enzymes. LM CMT is responsible for improving process intensification with both mammalian perfusion cell culture and downstream integrated continuous manufacturing (with focus on data science and automation). This job posting covers opportunities for interns in all the three technical areas above.

Number of intern openings: 3

The summer interns will be exposed to:

• In NES, recombinant protein expression optimization. Specifically, research on various building blocks of an expression cassette in one of our yeast expression systems, with a goal to maximize the production. The study could include but not limited to molecular cloning, strain construction, small scale cell growth, protein expression, and analysis.

• In LM CMT upstream, fundamentals of process intensification and continuous processing of biologics, expertise in the Chinese Hamster Ovary (CHO) perfusion cell culture, including evaluation of novel cell retention devices.

• In LM CMT downstream, end-to-end integrated continuous biomanufacturing employing state-of-the-art approaches, including automation, data science and engineering technologies coordinating both production and process monitoring across multiple steps in parallel.

The interns will be responsible for accurate electronic notebook recording of experimental details and for analysis and interpretation of data that may be used for internal or external scientific publications which may follow from the internship. Interns will have the opportunity to gain further knowledge, and skill sets via refinement of laboratory skills, introduction to new experimental techniques, exposure to current challenges in research, and perspectives on the practical aspects of drug development. In addition, the intern student will have an opportunity to present their research results in both oral and written formats.

This is a full-time internship position wherein we are seeking intern candidates at all levels with strong academic performance, communication skills, teamwork, and the ability to work in a multi-functional and fast-paced environment.

NOTE: If a candidate is selected for an interview, the candidate should be prepared to submit letters of recommendation and a brief research statement and a copy of transcripts.

Education Requirements:

• Candidates must be a currently enrolled student pursuing a Bachelor's, Master's, or PhD degree in Chemistry, Biology (e.g. Cell Biology, Virology), Biochemistry, Engineering (Chemical, Mechanical, Computer, Electrical), Materials Science, Pharmaceutical Science or a related discipline.

Required Experience and Skills:

• Candidates must be available to work full-time for up to (12) consecutive weeks beginning in June of 2025

• Candidates must have completed at least (2) years of studies toward bachelor's degree by June 2025

Preferred Experience and Skills:

• Candidates should have significant interest in pharmaceuticals.

• Candidates should have basic laboratory skills (lab notebook recording, use of instrumentation, analysis and interpretation of data, and safe lab practices), research experience, along with a problem-solving attitude.

• Candidates should have a GPA of 3.0 or higher

• For NES, candidates should have a significant interest in molecular biology and strain engineering. Experience in experimental techniques such as molecular cloning, recombination expression of proteins, culturing of microbes, and analytical assays.

• For LM CMT upstream, candidates should have aseptic technics, cell culture experience, knowledge of perfusion cultures for continuous manufacturing.

• For LM CMT downstream, candidates should have familiarity with engineering tools such as computer-aided design (CAD) software, Distributed Control Systems (DCS)/ Programmable Logic Controllers (PLC), data historians and piping &Instrumentation Diagrams (P&IDs), data science and understanding of biologic purification process.

FTP2025

MRL2025

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

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Los Angeles Residents Only:We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

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Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

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Requisition ID:R318088